AMR and the National Strategic Action Plan on AMR

Why is AMR a concern?

Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi, and parasites evolve and no longer respond to antimicrobials, making infections harder to treat and increasing the risks of disease spread, severe illness, disability and death. AMR also undermines the treatment of noncommunicable diseases and can make surgeries and routine medical procedures riskier. Growing resistance threatens to reverse decades of progress in human and veterinary medicine, agriculture, food production, environmental protection, and sustainable development.

Singapore’s National Strategic Action Plan on AMR

In 2017, Singapore launched the first National Strategic Action Plan on AMR (NSAP) to combat the growing problem of AMR in Singapore and worldwide. Through the NSAP, Singapore has adopted a One Health approach to tackling AMR by integrating previously independent efforts across the human, animal, food, and environment sectors.  

The first NSAP achieved several positive outcomes including the introduction of public education on AMR and antibiotic use, capability enhancements for AMR surveillance across all sectors, increased cross-sectoral research and information sharing, and strengthened international collaboration on AMR.

Singapore’s second National Strategic Action Plan on AMR (NSAPv2), launched on 12 November 2025, represents Singapore’s renewed commitment to combat the threat of AMR. The NSAPv2 builds upon the groundwork laid by the first NSAP to further advance One Health collaboration and drive more measurable and targeted action on AMR.

NSAPv2 aims to prevent the emergence and reduce the spread of drug-resistant organisms, and preserve the effectiveness of antimicrobials through a One Health approach, protecting human, animal and environmental health in Singapore. It sets 8 targets to be achieved by 2030.

The NSAPv2 is supported by a Monitoring and Evaluation (M&E) Framework that tracks the implementation of the NSAPv2 and its effectiveness in fulfilling the mission.

The NSAPv2 was jointly developed by One Health AMR Workgroup which comprises the Communicable Diseases Agency (CDA), National Environment Agency (NEA), National Parks Board (NParks), PUB, Singapore’s National Water Agency, and Singapore Food Agency (SFA).

Read the NSAPv2 here and the M&E Framework here.

Read the first NSAP (2017) here.

About AMRCO

The Antimicrobial Resistance Coordinating Office (AMRCO), under CDA, was established in 2018 as a coordinating body to facilitate the implementation and monitoring of the NSAP, coordinate antimicrobial resistance efforts across different sectors, and serve as the secretariat for national AMR committees.